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李国洋
助理教授、研究员、博士生导师
电子邮箱:lgy@pku.edu.cn
工作经历:
2023/03至今,6163am银河线路,6163am银河线路力学与工程科学系,助理教授,研究员
2019/08-2022/12,哈佛大学/麻省总医院,Wellman光医学研究中心,博士后
教育经历:
2014/09-2019/07,清华大学,航天航空学院,博士
2010/09-2014/07,清华大学,航天航空学院,学士
研究兴趣:
致力于力学与声学、光学和生物医学的交叉研究,发展先进生物医学技术和医学诊断技术,以揭示生命活动的基础科学规律,满足临床医学对早期和精确诊断的需求。研究兴趣包括,活组织力学成像(光学相干层析弹性成像、超声弹性成像和布里渊显微成像等),神经系统力学调控,活性介质波动力学,实验技术的转化应用等。
研究成果:
发展了考虑活组织应力及微结构等复杂性质的力学成像理论模型,解决了临床实验重复性差的问题且为发展特定组织的力学成像方法奠定了基础;将力学成像频谱拓展为从Hz到GHz横跨九个量级,发展了力学模型驱动的图像重构算法,提升了分辨率和灵敏度;自主开发了超声弹性导波成像和超宽频光学相干弹性成像设备;初步揭示了力学成像在血管、肌骨和肿瘤等的临床应用,成果对行业发展产生影响。迄今为止,在《JMPS》(6篇)、《Sci Adv》、《IEEE Trans Med Imaging》和《Med Image Analysis》等上以第一/通讯作者身份发表论文24篇。获21项专利和2项软件著作权。7项专利实现转化应用。
奖励与荣誉:
哈佛-MIT生物光学暑期学校最佳导师奖(学生获杰出研究奖1/30),2021
中国力学学会优秀博士学位论文提名奖,2020
清华大学优秀博士学位论文,2019
全国生物力学学术会议大会优秀学术论文奖,2018
清华大学特等奖学金,2017
国家奖学金,2013,2015,2016,2017
清华大学优秀本科毕业论文,2014
全国周培源大学生力学竞赛一等奖,2013
学术兼职:
《Science China Physics, Mechanics & Astronomy》青年编委
《Wave Motion》客座编辑
招聘信息:
课题组长期招收博士/硕士研究生、博士后,欢迎本科生加入并参与科研项目(感兴趣者请通过邮件联系)。
部分论文列表:

(†共同一作,*通讯作者):

1. Zhang, Z.; Li, G.-Y.*; Jiang, Y.; Zheng, Y.; Gower, A.L.; Destrade, M.; Cao, Y.*; Noninvasive measurement of local stress inside soft materials with programmed shear waves, Science Advances, 2023, 9: eadd4082.

2. Li, G.-Y.*; Jiang, Y.; Zheng, Y.; Xu, W.; Zhang, Z.; Cao, Y.*; Arterial stiffness probed by dynamic ultrasound elastography characterizes waveform of blood pressure, IEEE Transactions on Medical Imaging, 2022, 41(6): 1510-1519.

3. Li, G.-Y.; Gower, A.L.; Destrade, M.*; Yun, S.-H.*; Non-destructive mapping of stress, strain and stiffness of thin elastically deformed materials, Communications Physics, 2022, 5: 231.

4. Feng, X.; Li, G.-Y.; Ramier, A.; Eltony, A.M.; Yun, S.-H.*; In vivo stiffness measurement of epidermis, dermis, and hypodermis using broadband Rayleigh-wave optical coherence elastography, Acta Biomaterialia, 2022, 146: 295-305.

5. Li, G.-Y.*; Feng, X.; Ramier, A.; Yun, S.-H.*; Supershear surface waves reveal prestress and anisotropy of soft materials, Journal of the Mechanics and Physics of Solids, 2022, 169: 105085.

6. Li, G.-Y.; Cao, Y.*; Backward Mach cone of shear waves induced by a moving force in soft anisotropic materials, Journal of the Mechanics and Physics of Solids, 2020, 138: 103896.

7. Li, G.-Y.; Zheng, Y.; Jiang, Y.-X.; Zhang, Z.; Cao, Y.*; Guided wave elastography of layered soft tissues, Acta Biomaterialia, 2019, 84: 293-304.

8. Li, G.-Y.; Xu, G.; Zheng, Y.; Cao, Y.*; Non-leaky modes and bandgaps of surface acoustic waves in wrinkled stiff-film/compliant-substrate bilayers, Journal of the Mechanics and Physics of Solids, 2018, 112: 239-252.

9. Li, G.-Y.; He, Q.; Mangan, R.; Xu, G.; Mo, C.; Luo, J.; Destrade, M.; Cao, Y.*; Guided waves in pre-stressed hyperelastic plates and tubes: Application to the ultrasound elastography of thin-walled soft materials, Journal of the Mechanics and Physics of Solids, 2017, 102: 67-79.

10. Li, G.-Y.; Cao, Y.*; Mechanics of ultrasound elastography, Proceedings of the Royal Society A-Mathematical Physical and Engineering Sciences, 2017, 473(2199): 20160841. (Invited review)

11. Li, G.-Y.; Zheng, Y.; Liu, Y.; Destrade, M.; Cao, Y.*; Elastic Cherenkov effects in transversely isotropic soft materials-I: Theoretical analysis, simulations and inverse method, Journal of the Mechanics and Physics of Solids, 2016, 96: 388-410.

12. Li, G.-Y.; He, Q.; Qian, L.-X.; Geng, H.; Liu, Y.; Yang, X.-Y.; Luo, J.; Cao, Y.*; Elastic Cherenkov effects in transversely isotropic soft materials-II: Ex vivo and in vivo experiments, Journal of the Mechanics and Physics of Solids, 2016, 94: 181-190.

13. Jiang, Y.; Li, G.-Y.; Qian, L.-X.; Hu, X.-D.; Liu, D.; Liang, S.; Cao, Y.*; Characterization of the nonlinear elastic properties of soft tissues using the supersonic shear imaging (SSI) technique: Inverse method, ex vivo and in vivo experiments, Medical Image Analysis, 2015, 20(1): 97-111.